Apoptosis of HeLa cells induced by cisplatin and its mechanism

Abstract

To study the apoptosis induced by cisplatin in cervical cancer cell line HeLa and its mechanism, cell growth inhibition of cisplatin on HeLa cells was analyzed by MTT assay. Cell apoptosis was examined by cytometry and Hoechst33258 staining after treatment with cisplatin. The effects of cisplatin on transcription of E6 were analyzed by RT-PCR. The protein… (More)
DOI: 10.1007/s11596-008-0221-7

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@article{2008ApoptosisOH, title={Apoptosis of HeLa cells induced by cisplatin and its mechanism}, author={Youqing Liu 柳友清 and Hui Xing 邢辉 and Xiaobing Han 韩晓兵 and Xiaoyan Shi 石小燕 and Fengqi Liang 梁缝奇 and Gang Cheng 陈刚 and Yunping Lu 卢运萍 and Ding Ma 马丁}, journal={Journal of Huazhong University of Science and Technology [Medical Sciences]}, year={2008}, volume={28}, pages={197-199} }