Apoptosis occurs more frequently in intraductal carcinoma than in infiltrating duct carcinoma of human breast cancer and correlates with altered p53 expression: detected by terminal-deoxynucleotidyl-transferase-mediated dUTP-FITC nick end labelling (TUNEL).

@article{Harn1997ApoptosisOM,
  title={Apoptosis occurs more frequently in intraductal carcinoma than in infiltrating duct carcinoma of human breast cancer and correlates with altered p53 expression: detected by terminal-deoxynucleotidyl-transferase-mediated dUTP-FITC nick end labelling (TUNEL).},
  author={H. J. Harn and Kevin Shen and K C Yueh and Li Ing Ho and John C. L. Yu and Sin Chuen Chiu and Won Hyuck Lee},
  journal={Histopathology},
  year={1997},
  volume={31 6},
  pages={534-9}
}
AIMS We examined the relationship between apoptosis and three different major stages of human breast carcinoma: intraductal carcinoma (DCIS), infiltrating duct carcinoma (IDC) and metastatic carcinoma in lymph nodes. We also determined the correlation between apoptosis and oestrogen receptor (ER), progesterone receptor (PR) and p53. METHODS AND RESULTS The study investigates the extent of apoptosis in 63 breast carcinomas by in-situ end-labelling, in formalin-fixed, paraffin-processed tissue… CONTINUE READING

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Measures of cell turnover (proliferation and apoptosis) and their association with survival in breast cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2001
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