Apoptosis level in developing T cells in the thymus

Abstract

163 The thymus as the central organ of the immune system is responsible for the maturation of T cells. It is assumed that the formation of the TTcell receptor (TCR) is accompanied by the destruction of over 95% of CD4 + CD8 + cells. This hypothesis is based on the results of studies obtained in 1960–1970 in vitro, which were extrapolated to the processes in… (More)
DOI: 10.1134/S1607672915030060

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