Apoptosis induction of human prostate carcinoma cells by cordycepin through reactive oxygen species‑mediated mitochondrial death pathway.

@article{Lee2013ApoptosisIO,
  title={Apoptosis induction of human prostate carcinoma cells by cordycepin through reactive oxygen species‑mediated mitochondrial death pathway.},
  author={Hye Hyeon Lee and Cheol Park and Jin-Woo Jeong and Min Jeong Kim and M. J. Seo and Byoung Won Kang and Jeong Uck Park and Gi-young Kim and Byung Tae Choi and Young Hyun Choi and Yong Kee Jeong},
  journal={International journal of oncology},
  year={2013},
  volume={42 3},
  pages={1036-44}
}
Cordycepin is the main functional component of Cordyceps militaris, which has been widely used in oriental traditional medicine. This compound has been shown to possess many pharmacological properties, such as enhancing the body's immune function, and anti-inflammatory, anti-aging and anticancer effects. In the present study, we investigated the apoptotic effects of cordycepin in human prostate carcinoma cells. We found that treatment with cordycepin significantly inhibited cell growth by… CONTINUE READING