Apoptosis induction by silica nanoparticles mediated through reactive oxygen species in human liver cell line HepG2.

@article{Ahmad2012ApoptosisIB,
  title={Apoptosis induction by silica nanoparticles mediated through reactive oxygen species in human liver cell line HepG2.},
  author={Javed Ahmad and M. Basheer Ahamed and Mohd Javed Akhtar and Salman A. Alrokayan and Maqsood Ahmed Siddiqui and Javed Musarrat and Abdulaziz A. Al-Khedhairy},
  journal={Toxicology and applied pharmacology},
  year={2012},
  volume={259 2},
  pages={160-8}
}
Silica nanoparticles are increasingly utilized in various applications including agriculture and medicine. In vivo studies have shown that liver is one of the primary target organ of silica nanoparticles. However, possible mechanisms of hepatotoxicity caused by silica nanoparticles still remain unclear. In this study, we explored the reactive oxygen species (ROS) mediated apoptosis induced by well-characterized 14nm silica nanoparticles in human liver cell line HepG2. Silica nanoparticles (25… CONTINUE READING
48 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 48 extracted citations

Similar Papers

Loading similar papers…