Apoptosis induction by glycoprotein isolated from Laminaria japonica is associated with down-regulation of telomerase activity and prostaglandin E2 synthesis in AGS human gastric cancer cells.

@article{Han2011ApoptosisIB,
  title={Apoptosis induction by glycoprotein isolated from Laminaria japonica is associated with down-regulation of telomerase activity and prostaglandin E2 synthesis in AGS human gastric cancer cells.},
  author={Min Ho Han and Gi Young Kim and Sung-Kwon Moon and W. -G. Kim and T G Nam and Young Hyun Choi},
  journal={International journal of oncology},
  year={2011},
  volume={38 2},
  pages={577-84}
}
Glycoprotein isolated from Laminaria japonica (LJGP) is known to exhibit significant cytotoxic activity against human cancer cells; however, the mechanisms of its cytoxicity are poorly understood. In this study, we investigated further possible mechanisms by which LJGP exerts its anti-cancer action in cultured human gastric carcinoma AGS cells. LJGP… CONTINUE READING