Apoptosis induced by vitamin A signaling is crucial for connecting the ureters to the bladder

@article{Batourina2005ApoptosisIB,
  title={Apoptosis induced by vitamin A signaling is crucial for connecting the ureters to the bladder},
  author={Ekatherina Batourina and Sheaumei Tsai and Sarah R. Lambert and Preston C. Sprenkle and Renata Viana and Sonia Dutta and Terry W. Hensle and Fengwei Wang and Karen A Niederreither and Andrew P. McMahon and Thomas J Carroll and Cathy Lee Mendelsohn},
  journal={Nature Genetics},
  year={2005},
  volume={37},
  pages={1082-1089}
}
Removal of toxic substances from the blood depends on patent connections between the kidney, ureters and bladder that are established when the ureter is transposed from its original insertion site in the male genital tract to the bladder. This transposition is thought to occur as the trigone forms from the common nephric duct and incorporates into the bladder. Here we re-examine this model in the context of normal and abnormal development. We show that the common nephric duct does not… CONTINUE READING