Apoptosis in the pathogenesis and treatment of disease

@article{Thompson1995ApoptosisIT,
  title={Apoptosis in the pathogenesis and treatment of disease},
  author={C. Thompson},
  journal={Science},
  year={1995},
  volume={267},
  pages={1456 - 1462}
}
In multicellular organisms, homeostasis is maintained through a balance between cell proliferation and cell death. Although much is known about the control of cell proliferation, less is known about the control of cell death. Physiologic cell death occurs primarily through an evolutionarily conserved form of cell suicide termed apoptosis. The decision of a cell to undergo apoptosis can be influenced by a wide variety of regulatory stimuli. Recent evidence suggests that alterations in cell… Expand
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References

SHOWING 1-10 OF 145 REFERENCES
Cell death by apoptosis and its protective role against disease.
  • 436
Apoptosis: the physiologic pathway of cell death.
  • 61
Autoimmune disease. A problem of defective apoptosis.
  • 242
Bcl-2 and the regulation of programmed cell death
  • J. Reed
  • Medicine, Biology
  • The Journal of cell biology
  • 1994
  • 2,268
  • PDF
Cell death: the significance of apoptosis.
  • 7,353
...
1
2
3
4
5
...