Apoptosis in the pathogenesis and treatment of disease.

@article{Thompson1995ApoptosisIT,
  title={Apoptosis in the pathogenesis and treatment of disease.},
  author={Craig B Thompson},
  journal={Science},
  year={1995},
  volume={267 5203},
  pages={1456-62}
}
In multicellular organisms, homeostasis is maintained through a balance between cell proliferation and cell death. Although much is known about the control of cell proliferation, less is known about the control of cell death. Physiologic cell death occurs primarily through an evolutionarily conserved form of cell suicide termed apoptosis. The decision of a cell to undergo apoptosis can be influenced by a wide variety of regulatory stimuli. Recent evidence suggests that alterations in cell… CONTINUE READING

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