Apoptosis in nonalcoholic fatty liver disease: diagnostic and therapeutic implications.

@article{Alkhouri2011ApoptosisIN,
  title={Apoptosis in nonalcoholic fatty liver disease: diagnostic and therapeutic implications.},
  author={Naim Alkhouri and Christine Carter-Kent and Ariel E Feldstein},
  journal={Expert review of gastroenterology & hepatology},
  year={2011},
  volume={5 2},
  pages={201-12}
}
Pathological increases in cell death in the liver as well as in peripheral tissues has emerged as an important mechanism involved in the development and progression of nonalcoholic fatty liver disease (NAFLD). An increase in hepatocyte cell death by apoptosis is typically present in patients with NAFLD and in experimental models of steatohepatitis, while an increase in adipocyte cell death in visceral adipose tissue may be an important mechanism triggering insulin resistance and hepatic… CONTINUE READING