Apoptosis in murine norovirus-infected RAW264.7 cells is associated with downregulation of survivin.

@article{Bok2009ApoptosisIM,
  title={Apoptosis in murine norovirus-infected RAW264.7 cells is associated with downregulation of survivin.},
  author={Karin Bok and Victor G. Prikhodko and Kim Y Green and Stanislav V. Sosnovtsev},
  journal={Journal of virology},
  year={2009},
  volume={83 8},
  pages={3647-56}
}
Noroviruses (NVs) are recognized as a major cause of nonbacterial gastroenteritis in humans. Studies of the human NVs continue to be hampered by the inability to propagate them in any cell culture system. Until recently, most data concerning NV replication were derived from studies of feline calicivirus and rabbit hemorrhagic disease virus, which are cultivable members of the family Caliciviridae. From such studies, it was proposed that caliciviruses induce apoptosis to facilitate the… CONTINUE READING
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