Apoptosis in motion. An apical, P35-insensitive caspase mediates programmed cell death in insect cells.

Abstract

Activation of caspases by proteolytic processing is a critical step during apoptosis in metazoans. Here we use high resolution time lapse microscopy to show a tight link between caspase activation and the morphological events delineating apoptosis in cultured SF21 cells from the moth Spodoptera frugiperda, a model insect system. The principal effector… (More)

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