Apoptosis in liver diseases--detection and therapeutic applications.

  title={Apoptosis in liver diseases--detection and therapeutic applications.},
  author={Saeid Ghavami and Mohammad Kazem Hashemi and Kamran Kadkhoda and Seyed Moayed Alavian and Graham Bay and Marek Los},
  journal={Medical science monitor : international medical journal of experimental and clinical research},
  volume={11 11},
The liver is continuously exposed to a large antigenic load that includes pathogens, toxins, tumor cells and dietary antigens. Amongst the hepatitis viruses, only hepatitis B virus (HBV) and hepatitis C virus (HCV) cause chronic hepatitis, which can progress to cirrhosis and hepatocellular carcinoma. Of the different antiviral defense systems employed by the tissue, apoptosis significantly contributes to the prevention of viral replication, dissemination, and persistence. Loss of tolerance to… CONTINUE READING
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