Apoptosis in leukemia cells is accompanied by alterations in the levels and localization of nucleolin.

@article{Mi2003ApoptosisIL,
  title={Apoptosis in leukemia cells is accompanied by alterations in the levels and localization of nucleolin.},
  author={Yingchang Mi and Shelia D. Thomas and Xiaohua Xu and Lavona K. Casson and Donald M. Miller and Paula J. Bates},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 10},
  pages={8572-9}
}
Molecular defects in apoptotic pathways are thought to often contribute to the abnormal expansion of malignant cells and their resistance to chemotherapy. Therefore, a comprehensive knowledge of the mechanisms controlling induction of apoptosis and subsequent cellular disintegration could result in improved methods for prognosis and treatment of cancer. In… CONTINUE READING