Apoptosis in alcoholic and nonalcoholic steatohepatitis.

  title={Apoptosis in alcoholic and nonalcoholic steatohepatitis.},
  author={Ariel E Feldstein and Gregory J. Gores},
  journal={Frontiers in bioscience : a journal and virtual library},
Alcohol liver disease (ALD) as well as nonalcoholic fatty liver disease (NAFLD) are two of the most common forms of chronic liver disease worldwide and may progress to cirrhosis and end stage liver disease. ALD and NAFLD seem to share many pathophysiologic mechanisms with the accumulation of lipids in the liver being the first step in the development of both conditions. While mitochondrial dysfunction and production of reactive oxygen species seem to play an important role in the progression… CONTINUE READING
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