Apoptosis in a canine model of acute Chagasic myocarditis.

  title={Apoptosis in a canine model of acute Chagasic myocarditis.},
  author={Jun Zhang and Zilton de Ara{\'u}jo Andrade and Zhao Xiang Yu and S{\^o}nia Gumes Andrade and Kazuyo Takeda and M Sadirgursky and V{\'i}ctor J. Ferrans},
  journal={Journal of molecular and cellular cardiology},
  volume={31 3},
Histologic, ultrastructural and nick end labeling studies were made to evaluate the occurrence of apoptosis in the hearts of dogs with acute myocarditis due to experimental infection with T. cruzi. The best results for the detection of apoptosis by nick end labeling were obtained by a method combining the use of terminal deoxynucleotidyl transferase, CoCl2 and fluorescein-conjugated deoxyuridine triphosphate, followed by counterstaining of DNA with 4'6-diamidino-2-phenylindole (DAPI) and… CONTINUE READING


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