Corpus ID: 37176604

Apoptosis dysregulation in human gastric carcinomas: relationship to anti- and pro-apoptotic protein expression.

  title={Apoptosis dysregulation in human gastric carcinomas: relationship to anti- and pro-apoptotic protein expression.},
  author={Wesam A. Nasif and H. M. El-emshaty and M. Lotfy and K. Zalata and N. G. Elhak},
  journal={Asian Pacific journal of cancer prevention : APJCP},
  volume={8 1},
Apoptosis and the genes regulating this process have recently become a focus of interest in the study of cancer development and progression. Both Bcl-2 and Bax are transcriptional targets for the tumor supressor protein, p53, which induces cell cycle arrest or apoptosis in response to DNA damage. The coordinate performance of these molecules is crucial for controlling life or death of a cell. Correlations between apoptosis and protein expression of genes controlling this process including Bcl-2… Expand
6 Citations


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