Apoptosis as a specific biomarker of diazinon toxicity in NTera2-D1 cells.

@article{Aluigi2010ApoptosisAA,
  title={Apoptosis as a specific biomarker of diazinon toxicity in NTera2-D1 cells.},
  author={Maria Grazia Aluigi and Chiara A. Guida and Carla Falugi},
  journal={Chemico-biological interactions},
  year={2010},
  volume={187 1-3},
  pages={299-303}
}
The NTera2/D1 (NT2) cell line, which was derived from a human teratocarcinoma, exhibits properties that are characteristics of a committed neuronal precursor at an early stage of differentiation. Its property to express a whole set of molecules related to the cholinergic neurotransmission system, including active acetylcholinesterase (AChE, EC 3.1.1.7) makes it a good alternative model for testing the effects of neurotoxic compounds, such as organophosphorus (OP) insecticides, whose primary… CONTINUE READING

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