Apoptosis and the cell cycle in Xenopus laevis: PHA and PMA exposure of splenocytes.

@article{McMahan1999ApoptosisAT,
  title={Apoptosis and the cell cycle in Xenopus laevis: PHA and PMA exposure of splenocytes.},
  author={Rachel McMahan and Rachel O Johnson and Laurens N. Ruben and Richard H Clothier},
  journal={Immunology letters},
  year={1999},
  volume={70 3},
  pages={179-83}
}
T cell receptor (TCR) ligation and protein kinase C (PKC) activation stimulate proliferation and modulate apoptosis in both mammalian and amphibian lymphocytes. The potential relationship between apoptosis and the cell cycle in mature Xenopus laevis splenic lymphocytes is addressed by monitoring apoptosis and DNA synthesis over time, using incorporation of… CONTINUE READING