Apoptosis and neurogenesis after transient hypoxia in the developing rat brain.

@article{Daval2004ApoptosisAN,
  title={Apoptosis and neurogenesis after transient hypoxia in the developing rat brain.},
  author={J. -L. Daval and Paul Vert},
  journal={Seminars in perinatology},
  year={2004},
  volume={28 4},
  pages={
          257-63
        }
}
Perinatal brain damage following a hypoxic-ischemic episode has been considered for a long time as an irreversible phenomenon. However, recent studies have shown that various insults may induce de novo neurogenesis in the adult rodent brain. The present study tested the hypothesis that acute hypoxia may trigger neurogenesis in the developing brain. In vitro, the influence of transient hypoxia was analyzed on the outcome of embryonic rat neurons in culture. In vivo, the temporal profile of brain… CONTINUE READING

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