Apoptosis and necrosis in liver disease.

  title={Apoptosis and necrosis in liver disease.},
  author={Hartmut Jaeschke and Jaspreet S Gujral and Mary Lynn Bajt},
  journal={Liver international : official journal of the International Association for the Study of the Liver},
  volume={24 2},
Liver cell injury and cell death is a prominent feature in all liver disease processes. During the last 5-10 years, most research activities focused almost exclusively on evaluating apoptotic cell death and the corresponding intracellular signaling pathways. Although this effort led to substantial progress in our understanding of the mechanisms of apoptosis, it also created substantial confusion regarding the predominant mode of cell death and the relevance of apoptosis in a variety of liver… CONTINUE READING


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