Apoptosis and necrosis in health and disease: role of mitochondria.

  title={Apoptosis and necrosis in health and disease: role of mitochondria.},
  author={A. Nieminen},
  journal={International review of cytology},
  • A. Nieminen
  • Published 2003 in International review of cytology
Mitochondria play an important role in both the life and death of cells. Mitochondria are the powerhouse of the cell, providing over 90% of adenosine triphosphate (ATP) consumed by the cell. Mitochondrial energy production, however, is disrupted in various pathological situations leading to cellular Injury. The mechanisms causing the injury are turning out to be more complex than originally expected. For instance, calcium, oxidant chemicals, ischemia/ reperfusion, and a range of other agents… CONTINUE READING


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