Apoptosis and loss of renal tissue in polycystic kidney diseases.

@article{Woo1995ApoptosisAL,
  title={Apoptosis and loss of renal tissue in polycystic kidney diseases.},
  author={D Woo},
  journal={The New England journal of medicine},
  year={1995},
  volume={333 1},
  pages={18-25}
}
  • D Woo
  • Published 1995 in The New England journal of medicine
BACKGROUND Polycystic kidney disease is characterized by the enlargement of renal cysts, interstitial fibrosis, and gradual loss of normal renal tissue in association with progressive deterioration of renal function. The process causing the progressive loss of renal tissue is unknown, but it could be the result of a form of programmed cell death known as apoptosis. METHODS We assayed apoptotic DNA fragmentation in normal and polycystic kidneys biochemically by gel electrophoresis and… CONTINUE READING

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