Apoptosis and its modulation during infection with Toxoplasma gondii: molecular mechanisms and role in pathogenesis.

@article{Lder2005ApoptosisAI,
  title={Apoptosis and its modulation during infection with Toxoplasma gondii: molecular mechanisms and role in pathogenesis.},
  author={Carsten G{\"u}nter Kurt L{\"u}der and U. Gross},
  journal={Current topics in microbiology and immunology},
  year={2005},
  volume={289},
  pages={219-37}
}
Infection with the obligate intracellular protozoan Toxoplasma gondii leads to lifelong persistence of the parasite in its mammalian hosts including humans. Apoptosis plays crucial roles in the interaction between the host and the parasite. This includes innate and adaptive defense mechanisms to restrict intracellular parasite replication as well as regulatory functions to modulate the host's immune response. Not surprisingly, however, T. gondii also extensively modifies apoptosis of its own… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 35 extracted citations

Similar Papers

Loading similar papers…