Apoptosis and glutathione: beyond an antioxidant

  title={Apoptosis and glutathione: beyond an antioxidant},
  author={Renato R. Franco and John Anthony Cidlowski},
  journal={Cell Death and Differentiation},
Apoptosis is a conserved homeostatic process critical for organ and tissue morphogenesis, development, and senescence. This form of programmed cell death also participates in the etiology of several human diseases including cancer, neurodegenerative, and autoimmune disorders. Although the signaling pathways leading to the progression of apoptosis have been extensively characterized, recent studies highlight the regulatory role of changes in the intracellular milieu (permissive apoptotic… CONTINUE READING
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