Apoptosis and bcl-2 expression in normal human endometrium, endometriosis and adenomyosis.

@article{Jones1998ApoptosisAB,
  title={Apoptosis and bcl-2 expression in normal human endometrium, endometriosis and adenomyosis.},
  author={R K Jones and Roger F. Searle and Judith N. Bulmer},
  journal={Human reproduction},
  year={1998},
  volume={13 12},
  pages={3496-502}
}
Apoptosis has been implicated in the pathogenesis of several diseases and is partly regulated by bcl-2, which blocks the apoptotic pathway and promotes cell survival. Apoptosis and bcl-2 expression were examined in paired eutopic and ectopic endometrium from women with endometriosis (n = 30 samples) or adenomyosis (n = 15 samples) and compared with control endometrium (n = 30 samples). Apoptotic cells were detected using the dUTP nick-end labelling (TUNEL) assay for DNA fragmentation; bcl-2… CONTINUE READING

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