Apoptosis and Sjögren syndrome.

  title={Apoptosis and Sj{\"o}gren syndrome.},
  author={Paolo Manganelli and Pieranna Fietta},
  journal={Seminars in arthritis and rheumatism},
  volume={33 1},
OBJECTIVE To examine the role of apoptosis in the pathogenesis of Sjögren syndrome (SS), a chronic autoimmune disease characterized by the infiltration of mononuclear cells in the salivary and lacrimal glands, leading to the destruction of the parenchymal tissue. METHODS A detailed search via MEDLINE (PubMed) and Biosis, covering the period from January 1994 to July 2002, was accomplished, combining the key terms SS and apoptosis. A qualitative review of the articles was undertaken and the… CONTINUE READING


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