Apoptosis and Caspase 3 Pathway Role on Anti-Proliferative Effects of Scrophulariaoxy Sepala Methanolic Extract on Caco-2 Cells.

@article{Namvaran2017ApoptosisAC,
  title={Apoptosis and Caspase 3 Pathway Role on Anti-Proliferative Effects of Scrophulariaoxy Sepala Methanolic Extract on Caco-2 Cells.},
  author={Ali Namvaran and Mehdi Fazeli and Safar Farajnia and Gholamreza Hamidian and Hassan Rezazadeh},
  journal={Drug research},
  year={2017},
  volume={67 9},
  pages={
          547-552
        }
}
Colorectal cancer is one the most important malignancies worldwide and finding new treatment option for this cancer is of high priority. Natural compounds are common source of drugs for treatment of various diseases including cancers. The aim of this study was to investigate the effects of Scrophularia oxysepala extract on Caco-2 cells and explore the possible role of caspase 3 pathway in inducing cell death in this cancer cells in compare with chemotherapy agents of cisplatin and capecitabine… 
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