Apoptosis: The importance of being eaten

@article{Ren1998ApoptosisTI,
  title={Apoptosis: The importance of being eaten},
  author={Yi Ren and John Savill},
  journal={Cell Death and Differentiation},
  year={1998},
  volume={5},
  pages={563-568}
}
In vivo, cells undergoing apoptosis are usually recognised and swiftly ingested by macrophages or neighbouring cells acting as semi-professional phagocytes. This review debates evidence that the contents of apoptotic cells represent a danger to the organism, being capable of injuring tissue directly or triggering autoimmune responses, concluding that phagocytic clearance of intact apoptotic cells is a safe disposal route. Indeed, new data suggest that, in certain circumstances, phagocytes… CONTINUE READING

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