Apoptosis: Opening PANdora's BoX


Extracellular nucleotides have been reported to act as a 'find-me' signal in the context of phagocyte recruitment by apoptotically dying cells. A new study now examines the mechanisms of nucleotide release during apoptosis and describes the hemichannel-forming protein pannexin 1 as a crucial player in this scenario. 
DOI: 10.1016/j.cub.2010.12.018


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