Apoptosis, autophagy, necroptosis, and cancer metastasis

Abstract

Metastasis is a crucial hallmark of cancer progression, which involves numerous factors including the degradation of the extracellular matrix (ECM), the epithelial-to-mesenchymal transition (EMT), tumor angiogenesis, the development of an inflammatory tumor microenvironment, and defects in programmed cell death. Programmed cell death, such as apoptosis… (More)
DOI: 10.1186/s12943-015-0321-5

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