Apoptosis, angiogenesis, inflammation, and oxidative stress: basic interactions in patients with early and metastatic breast cancer

@article{Hamed2012ApoptosisAI,
  title={Apoptosis, angiogenesis, inflammation, and oxidative stress: basic interactions in patients with early and metastatic breast cancer},
  author={Enas Ahmed Hamed and Madeha M. Zakhary and Doaa Wadeeh Maximous},
  journal={Journal of Cancer Research and Clinical Oncology},
  year={2012},
  volume={138},
  pages={999-1009}
}
Breast cancer (BC) is a complex, multi-stage disease involving deregulation of different signaling cascades. The present study was conducted to determine the extent of apoptosis, angiogenesis, inflammation, and oxidative stress in patients with different stages of BC as an approach to disease biological behavior. Therefore, plasma levels of soluble (s) Fas, bcl-2 as antiapoptotic indices; interleukin (IL)-8, tumor necrosis factor (TNF)-α as apoptotic, inflammatory, angiogenic indices; lipid… CONTINUE READING