Apoptin enhances the oncolytic properties of Newcastle disease virus.

Abstract

OBJECTIVE Naturally occurring strains of Newcastle disease virus (NDV) have demonstrated the potential to kill cancer cells in both preclinical and clinical studies. Previous studies showed that apoptin, the VP3 protein of chicken infectious anemia virus, is a p53-independent, Bcl-2-insensitive apoptotic protein with the ability to specifically induce… (More)
DOI: 10.1159/000328325

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