Apoprotein E as a lipid transport and signaling protein in the blood, liver, and artery wall.

@article{Getz2009ApoproteinEA,
  title={Apoprotein E as a lipid transport and signaling protein in the blood, liver, and artery wall.},
  author={G. S. Getz and Catherine A. Reardon},
  journal={Journal of lipid research},
  year={2009},
  volume={50 Suppl},
  pages={S156-61}
}
Apoprotein E (apoE) is synthesized by a number of tissues including the liver, brain, adipose tissue, and artery wall. The majority of apoE is found in the plasma associated with specific lipoprotein subclasses and is derived primarily from the liver. However the fact that apoE expression is sustained in nonhepatic tissues suggests that the local production must have some unique functional attribute. ApoE is involved in many steps in lipid and lipoprotein homeostasis, for the triglyceride-rich… CONTINUE READING

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