Apolipoprotein e genotype, cortisol, and cognitive function in community-dwelling older adults.


BACKGROUND Elevated cortisol indicates stress and may be a risk factor for cognitive decline in aging. Genetic factors may influence individual vulnerability to the adverse effects of stress on cognitive function in aging. METHOD The authors investigated whether the gene-environment interaction between the genotype for the apolipoprotein E gene (APOE) and… (More)
DOI: 10.1176/appi.ajp.2008.07091532