Apolipoprotein M Gene (APOM) Polymorphism Modifies Metabolic and Disease Traits in Type 2 Diabetes

  title={Apolipoprotein M Gene (APOM) Polymorphism Modifies Metabolic and Disease Traits in Type 2 Diabetes},
  author={Jun-wei Zhou and Stephen Kwok-Wing Tsui and Maggie C. Y. Ng and Hua Geng and S H Li and Wing-Yee So and Ronald C. W. Ma and Ying Wang and Qian Tao and Zhen-yu Chen and Juliana Chung Ngor Chan and Yuan-Yuan Ho},
  booktitle={PloS one},
This study aimed at substantiating the associations of the apolipoproein M gene (APOM) with type 2 diabetes (T2D) as well as with metabolic traits in Hong Kong Chinese. In addition, APOM gene function was further characterized to elucidate its activity in cholesterol metabolism. Seventeen APOM SNPs documented in the NCBI database were genotyped. Five SNPs were confirmed in our study cohort of 1234 T2D and 606 control participants. Three of the five SNPs rs707921(C+1871A), rs707922(G+1837T) and… CONTINUE READING


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Publications referenced by this paper.
Showing 1-10 of 29 references

[Distribution characters and linkage disequilibrium analysis of APOM gene polymorphisms in Han population of North China].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics • 2007
View 8 Excerpts
Highly Influenced

Evaluation of Apolipoprotein M Serum Concentration as a Biomarker of HNF1alpha MODY

J Skupien, G Kepka, S Gorczynska-Kosiorz, A Gebska, T Klupa
Rev Diabet Stud • 2007
View 1 Excerpt
Highly Influenced

/ impaired glucose homeostasis susceptibility genes in the Chinese : significant linkage to chromosome 6 q 21 - q 23 and chromosome 1 q 21 - q 24

GQ Jiao, ZX Yuan, YS Xue, CJ Yang, CB Lu

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