Apolipoprotein M Gene (APOM) Polymorphism Modifies Metabolic and Disease Traits in Type 2 Diabetes

@inproceedings{Zhou2011ApolipoproteinMG,
  title={Apolipoprotein M Gene (APOM) Polymorphism Modifies Metabolic and Disease Traits in Type 2 Diabetes},
  author={Jun-wei Zhou and Stephen Kwok-Wing Tsui and Maggie C. Y. Ng and Hua Geng and S H Li and Wing-Yee So and Ronald C. W. Ma and Ying Wang and Qian Tao and Zhen-yu Chen and Juliana Chung Ngor Chan and Yuan-Yuan Ho},
  booktitle={PloS one},
  year={2011}
}
This study aimed at substantiating the associations of the apolipoproein M gene (APOM) with type 2 diabetes (T2D) as well as with metabolic traits in Hong Kong Chinese. In addition, APOM gene function was further characterized to elucidate its activity in cholesterol metabolism. Seventeen APOM SNPs documented in the NCBI database were genotyped. Five SNPs were confirmed in our study cohort of 1234 T2D and 606 control participants. Three of the five SNPs rs707921(C+1871A), rs707922(G+1837T) and… CONTINUE READING

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