Apolipoprotein E polymorphism is associated with age of onset in schizophrenia

  title={Apolipoprotein E polymorphism is associated with age of onset in schizophrenia},
  author={Olli Kampman and Sami Anttila and Ari Illi and Kari M. Mattila and Riikka Rontu and Esa Veli Juhani Leinonen and Terho Lehtim{\"a}ki},
  journal={Journal of Human Genetics},
AbstractThe aims of the study were to investigate the relationship between Apolipoprotein E (APOE) polymorphism, risk of schizophrenia, treatment response to conventional anti-psychotics, and age of onset in schizophrenia. The sample comprised 94 Finnish patients with a DSM-IV diagnosis of schizophrenia. Forty-three of the patients were good responders to conventional anti-psychotics and 51 were classified as non-responders. The control group consisted of 98 healthy blood donors. The APOE… CONTINUE READING
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