Apolipoprotein E polymorphism influences lipid phenotypes in Chinese families with familial combined hyperlipidemia.


BACKGROUND Apolipoprotein E (apoE) polymorphism is associated with changes in the lipoprotein profile of individuals with familial combined hyperlipidemia (FCHL), but its effects on the lipoprotein profiles of members of Chinese families with FCHL remain uncertain. METHODS AND RESULTS 43 FCHL families (n=449) and 9 normolipidemic families (n=73) were… (More)


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