Apolipoprotein E polymorphism, a marker of disease severity in primary biliary cirrhosis?

@article{Corpechot2001ApolipoproteinEP,
  title={Apolipoprotein E polymorphism, a marker of disease severity in primary biliary cirrhosis?},
  author={Christophe Corpechot and Pascale Benlian and V{\'e}ronique Barbu and Olivier Chazouilleres and Ren{\'e}e Eug{\'e}nie Poupon},
  journal={Journal of hepatology},
  year={2001},
  volume={35 3},
  pages={324-8}
}
BACKGROUND/AIMS To determine whether the apolipoprotein E (apo-E) polymorphism is associated with the risk of primary biliary cirrhosis (PBC), the severity of the disease and its response to ursodeoxycholic acid (UDCA) therapy. METHODS The apo-E genotype was determined in 72 PBC patients. Genotype and allele distributions were compared with those found in the French general population. Laboratory parameters obtained before and after 1- and 4-year UDCA treatment were compared according to the… CONTINUE READING

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