Apolipoprotein E in hyperlipidemia.

  title={Apolipoprotein E in hyperlipidemia.},
  author={C C Walden and Robert A Hegele},
  journal={Annals of internal medicine},
  volume={120 12},
PURPOSE To review DNA analysis of apolipoprotein E used to assess patients with hyperlipidemia. DATA SOURCES AND STUDY SELECTION 44 basic science studies of molecular analysis; 42 basic science studies of the biochemical, cellular biological, and molecular biological features of apolipoprotein E; and 29 clinical investigational studies, meta-analyses, and case series of patients with mutations in apolipoprotein E. DATA EXTRACTION Methods of DNA analysis were reviewed, using specific… CONTINUE READING