Apolipoprotein E in animal models of CNS injury and in alzheimer's disease

@article{Poirier1994ApolipoproteinEI,
  title={Apolipoprotein E in animal models of CNS injury and in alzheimer's disease},
  author={Judes Poirier},
  journal={Trends in Neurosciences},
  year={1994},
  volume={17},
  pages={525-530}
}
Recent evidence indicates that apolipoprotein E (ApoE) plays a central role in the hippocampal response to injury. The co-ordinated expression of ApoE and its receptor, the ApoE/ApoB [low density lipoprotein (LDL)] receptor, appears to regulate the transport of cholesterol and phospholipids during the early and intermediate phases of the reinnervation process. During dendritic remodeling and synaptogenesis, neurons progressively repress the synthesis of cholesterol in favor of cholesterol… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 199 CITATIONS, ESTIMATED 43% COVERAGE

APOE, APOE promoter, and Tau genotypes and risk for concussion in college athletes.

  • Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine
  • 2008
VIEW 3 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Ceramide is responsible for the failure of compensatory nerve sprouting in apolipoprotein E knock-out mice.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2008
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

ApoE-dependent plasticity in Alzheimer’s disease

  • Journal of Molecular Neuroscience
  • 2004
VIEW 7 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

Olfactory function in apoE knockout mice

VIEW 1 EXCERPT
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

1995
2018

CITATION STATISTICS

  • 15 Highly Influenced Citations