Apolipoprotein E genotype and risk for development of cataract and age-related macular degeneration.

@article{Utheim2008ApolipoproteinEG,
  title={Apolipoprotein E genotype and risk for development of cataract and age-related macular degeneration.},
  author={\Oygunn Aass Utheim and Jon St{\aa}le Ritland and Tor Paaske Utheim and Thomas Espeseth and Stian Lydersen and Helge Rootwelt and Svein Ove Semb and Tor B Els{\aa}s},
  journal={Acta ophthalmologica},
  year={2008},
  volume={86 4},
  pages={401-3}
}
PURPOSE To study whether apolipoprotein E (APOE) genotypes are associated with risk for developing cataract and age-related macular degeneration (AMD). METHODS A sample of 88 healthy adults (50-75 years) genotyped for polymorphisms of APOE underwent an eye examination which included visual acuity (VA) testing, slit-lamp cataract evaluation, optical coherence tomography (OCT) and fundus photography, the last of which was analysed and graded for macular pathology at the Reading Centre… CONTINUE READING

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