Apolipoprotein E genotype and noncognitive symptoms in Alzheimer's disease.

@article{Levy1999ApolipoproteinEG,
  title={Apolipoprotein E genotype and noncognitive symptoms in Alzheimer's disease.},
  author={Mike L Levy and Jeffrey L. Cummings and Lynn A. Fairbanks and David L. Sultzer and Gary W. Small},
  journal={Biological psychiatry},
  year={1999},
  volume={45 4},
  pages={422-5}
}
BACKGROUND The apolipoprotein E (ApoE) epsilon 4 allele confers significant risk for Alzheimer's disease and is associated with a greater amyloid burden in the brain. Future treatments may target molecular mechanisms associated with this allele, and it is important to define any phenotypic characteristics that correspond to this genotype. We sought to clarify the relationship between ApoE status and noncognitive symptoms in Alzheimer's disease patients. METHODS Possible and probable Alzheimer… CONTINUE READING
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