Apolipoprotein E genotype and lifetime cognitive decline.

@article{Kozauer2008ApolipoproteinEG,
  title={Apolipoprotein E genotype and lifetime cognitive decline.},
  author={N. A. Kozauer and M. M. Mielke and Gary Kwun Chuen Chan and George W. Rebok and C. G. Lyketsos},
  journal={International psychogeriatrics},
  year={2008},
  volume={20 1},
  pages={109-23}
}
OBJECTIVE The relationship of apolipoprotein E (APOE) genotype to lifetime cognitive decline was examined over 22 years in a large community-based population study. METHOD The sample for the present study was derived from follow-up of a probability sample of the adult household residents of East Baltimore. From the Baltimore cohort of the Epidemiologic Catchment Area Study, genotype data were collected on 818 participants at the study's fourth wave between 2003 and 2004. Participants were… CONTINUE READING

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Although a clear association exists between APOE genotype and cognitive decline or dementia in late life , these findings suggest that over the lifespan the relationship between APOE and cognitive decline is more complicated .
Although a clear association exists between APOE genotype and cognitive decline or dementia in late life , these findings suggest that over the lifespan the relationship between APOE and cognitive decline is more complicated .
Although a clear association exists between APOE genotype and cognitive decline or dementia in late life , these findings suggest that over the lifespan the relationship between APOE and cognitive decline is more complicated .
Although a clear association exists between APOE genotype and cognitive decline or dementia in late life , these findings suggest that over the lifespan the relationship between APOE and cognitive decline is more complicated .
Although a clear association exists between APOE genotype and cognitive decline or dementia in late life , these findings suggest that over the lifespan the relationship between APOE and cognitive decline is more complicated .
Although a clear association exists between APOE genotype and cognitive decline or dementia in late life , these findings suggest that over the lifespan the relationship between APOE and cognitive decline is more complicated .
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