Apolipoprotein E genotype and deposits of Abeta40 and Abeta42 in Alzheimer disease.

@article{McNamara1998ApolipoproteinEG,
  title={Apolipoprotein E genotype and deposits of Abeta40 and Abeta42 in Alzheimer disease.},
  author={Melissa McNamara and Teresa G{\'o}mez-Isla and Bradley T. Hyman},
  journal={Archives of neurology},
  year={1998},
  volume={55 7},
  pages={1001-4}
}
OBJECTIVE To examine the differential deposition of amyloid beta (Abeta) peptide isoforms Abeta40 and Abeta42 in the Alzheimer disease (AD) brain in relation to the apolipoprotein E (APOE) genotype. BACKGROUND The APOE epsilon4 genotype is an inherited risk factor for AD and is associated with increased deposition of Abeta protein in the cerebral cortex… CONTINUE READING