Apolipoprotein E and obstructive sleep apnea: evaluating whether a candidate gene explains a linkage peak.

Abstract

Evidence from both linkage analyses and association-based analyses has implicated Apoliprotein E (ApoE) as a disease susceptibility locus for obstructive sleep apnea. To further assess the putative role of ApoE in sleep apnea, we performed genotyping, association, and linkage analyses in a cohort assembled to investigate the genetic epidemiology of sleep… (More)

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