Apolipoprotein E and alpha brain rhythms in mild cognitive impairment: a multicentric electroencephalogram study.

@article{Babiloni2006ApolipoproteinEA,
  title={Apolipoprotein E and alpha brain rhythms in mild cognitive impairment: a multicentric electroencephalogram study.},
  author={Claudio Babiloni and Luisa Benussi and Giuliano Binetti and Emanuele Cassetta and Gloria Dal Forno and Claudio Del Percio and Florinda Ferreri and Raffaele Ferri and Giovanni B. Frisoni and Roberta Ghidoni and Carlo Miniussi and Guido Rodriguez and Gian Luca Romani and Rosanna Squitti and Maria Carla Ventriglia and Paolo Maria Rossini},
  journal={Annals of neurology},
  year={2006},
  volume={59 2},
  pages={
          323-34
        }
}
OBJECTIVE Relationships between the apolipoprotein E epsilon4 allele and electroencephalographic (EEG) rhythmicity have been demonstrated in Alzheimer's disease (AD) patients but not in the preclinical stage prodromic to it, namely, mild cognitive impairment (MCI). The present multicentric EEG study tested the hypothesis that presence of epsilon4 affects sources of resting EEG rhythms in both MCI and AD subjects. METHODS We enrolled 89 MCI subjects (34.8% with epsilon4) and 103 AD patients… CONTINUE READING

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