Apolipoprotein E alleles in Cuban patients with mild cognitive impairment.

  title={Apolipoprotein E alleles in Cuban patients with mild cognitive impairment.},
  author={Viana Manrique Su{\'a}rez and Yuriem Fern{\'a}ndez and Elena del Carmen Ruiz L{\'o}pez and David Higginson Clarke and Maria A. Bobes and Ana Maria River{\'o}n and Lilia L{\'o}pez-C{\'a}novas},
  journal={American journal of Alzheimer's disease and other dementias},
  volume={29 3},
BACKGROUND Apolipoprotein E (ApoE) ε4 genotype is the most clearly documented risk factor for Alzheimer's disease (AD). Epidemiological studies demonstrate an accelerated rate of progression to dementia and AD in patients with mild cognitive impairment (MCI). We assessed the ApoE allele and genotypes frequencies in Cuban patients with MCI. METHODS We performed ApoE genotyping of 74 Cuban patients more than 65 years old. Cognitive assessments included the Mini-Mental State Examination (MMSE… CONTINUE READING
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