Apolipoprotein E alleles and risk of coronary disease. A meta-analysis.


A meta-analysis was undertaken to assess the impact of apolipoprotein E (apo E) alleles (epsilon 2, epsilon 3, and epsilon 4) on coronary disease in 14 published observational studies (9 clinical coronary disease and 5 coronary angiography). In comparison with epsilon 3, the epsilon 4 allele was associated with greater odds for coronary heart disease, and… (More)


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