Apolipoprotein E ε4 allele interacts with sex and cognitive status to influence all-cause and cause-specific mortality in U.S. older adults.

@article{Beydoun2013ApolipoproteinE,
  title={Apolipoprotein E ε4 allele interacts with sex and cognitive status to influence all-cause and cause-specific mortality in U.S. older adults.},
  author={May A Beydoun and Hind A. Beydoun and Jay S Kaufman and Yang Soo An and Susan M. Resnick and Richard O'Brien and Luigi Ferrucci and Alan B. Zonderman},
  journal={Journal of the American Geriatrics Society},
  year={2013},
  volume={61 4},
  pages={525-34}
}
OBJECTIVES To confirm associations of apolipoprotein E (ApoE) ε4 carrier status, sex, and time-dependent cognitive status with mortality risk and to investigate these joint effects of these associations in a cohort of community-dwelling U.S. adults. DESIGN Prospective cohort study. SETTING The Baltimore Longitudinal Study of Aging (BLSA). PARTICIPANTS Of 3,047 BLSA participants aged 17 to 98 at first visit (60.1% male), 1,704 with complete ApoE genotype data were included, of whom 1,461… CONTINUE READING
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